4 November

Morphogens

STUDENT PRESENTATION

Developmental dynamics of cell specification

  REVIEW:      Vincent S, Perrimon N. (2001) Fishing for morphogens. Nature 411: 535-6

   RESEARCH:     Chen Y, Schier AF. (2001). The zebrafish Nodal signal Squint functions as a morphogen. Nature 411:607-10.
9 November

Brain and Neuronal Differentiation
STUDENT PRESENTATION
 REVIEW: Dessaud E, McMahon AP, Briscoe J.
Development. 2008 Aug;135(15):2489-503. Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network.RESEARCH: Dessaud E, Yang LL, Hill K, Cox B, Ulloa F, Ribeiro A, Mynett A, Novitch BG, Briscoe J.
Nature. 2007 Nov 29;450(7170):717-20. Interpretation of the sonic hedgehog morphogen gradient by a temporal adaptation mechanism.
Chapter 12, Central nervous system, eye.
16 November

Paraxial mesoderm: Segmentation and myogenesis

STUDENT PRESENTATION

Chapter 14, Formation of somites and myogenesis

  REVIEW: Cooke, J. (1998). A gene that resuscitates a theory--somitogenesis and a molecular oscillator. Trends in Genetics 14: 85-88

 RESEARCH:       Palmeirim I, Henrique D, Ish-Horowicz D, Pourquie O. (1997). Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis. Cell 91:639-48.
18 November

Paraxial mesoderm in zebrafish

STUDENT PRESENTATION

Review: Stellabotte F, and Devoto SH (2007). The teleost dermomyotome.  Dev Dyn 236:2432-2443.
Research: Stellabotte F, Dobbs-McAuliffe B, Fernández DA, Feng X, and Devoto SH (2007). Dynamic somite cell rearrangements lead to distinct waves of myotome growth.  Development 134: 1253-1257.

2 December

Stem Cell Production

STUDENT PRESENTATION

TEXTBOOK: Chapter 21, Developmental Biology and Medicine

REVIEW: Epigenetic reprogramming and induced pluripotency.Hochedlinger K, Plath K. Development. 2009 Feb;136(4):509-23

RESEARCH: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.Takahashi K, Yamanaka S. Cell. 2006 Aug 25;126(4):663-76.
7 December

Stem cell therapy

STUDENT PRESENTATION

STUDENT PRESENTATION

RESEARCH: Dezawa M, Ishikawa H, Itokazu Y, Yoshihara T, Hoshino M, Takeda S, Ide C, Nabeshima Y.Bone marrow stromal cells generate muscle cells and repair muscle degeneration. Science. 2005 Jul 8;309(5732):314-7.

RESEARCH: Rideout WM 3rd, Hochedlinger K, Kyba M, Daley GQ, Jaenisch R. Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy. Cell. 2002 Apr 5;109(1):17-27.
14 December

Genetic Basis for Evolutionary Change

STUDENT PRESENTATION

REVIEW: Shubin NH, Dahn RD. (2004). Evolutionary biology: lost and found. Nature. 428:703-4.
RESEARCH: Shapiro MD, Marks ME, Peichel CL, Blackman BK, Nereng KS, Jonsson B, Schluter D, Kingsley DM. (2004). Genetic and developmental basis of evolutionary pelvic reduction in threespine sticklebacks. Nature. 428:717-23.